Sone-296 !!top!! May 2026

Is it a:

Serial console access (for debugging)

  1. Connect TTL USB-to-UART adapter: Adapter TX → Board RX, Adapter RX → Board TX, Ground → Ground.
  2. Configure terminal: 115200 baud, 8N1 (common default).
  3. Press reset to observe boot messages.

5. Clinical Development

5.1 Phase I (First‑in‑Human)

| Parameter | Details | |-----------|---------| | Study design | Open‑label, dose‑escalation (3 + 3), followed by expansion cohorts. | | Population | Adults with advanced solid tumors refractory to standard therapy. | | Dose range | 5 mg – 200 mg QD oral. | | Primary endpoints | Safety/tolerability, MTD, pharmacokinetics. | | Key secondary endpoints | Preliminary efficacy (RECIST response), pharmacodynamics (target inhibition in tumor biopsies). | | Status | Completed (2024); MTD = 150 mg QD, RP2D = 120 mg QD. | SONE-296

Abstract (150‑200 words)

A brief, one‑paragraph summary that states: Is it a: Serial console access (for debugging)