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Downloaded over 30,000 times and cited in over 500 peer-reviewed publications. AltAnalyze has hundreds of active users and is being actively developed as an open-source project.

AltAnalyze and dependent applications recieve funding from NIH National Cancer Institute (R01CA226802 and R21CA300922).

 


Manuscripts to Cite (Open Access Links)

AltAnalyze
AltAnalyze3
OncoSplice
Splicing NeoAntigen Finder
RNA-SPRINT
MultiPath-PSI
ICGS2
cellHarmony
DoubletDecon

 

 
AltAnalyze - Comprehensive Transcriptome Analysis

AltAnalyze is an easy-to-use application for the end-to-end analysis of single-cell (ICGS/ cellHarmony) and bulk RNA-Seq data. For splicing sensitive platforms (single cell/bulk RNA-Seq or microarrays), AltAnalyze identities alternative splicing events,impacted protein isoforms, domain composition and microRNA targeting. AltAnalyze automates every step of gene expression and splicing analysis other data (FASTQ processing, RMA summarization, batch-effect removal, QC, statistics, annotation, clustering, network creation, lineage characterization, alternative exon visualization, gene-set enrichement and more). AltAnalyze3 contains special methods for bulk and single-cell long-read analysis. Easy to follow video tutorials can be found here. Updates can be found on our blog and examples in our interactive browsers.

AltAnalyze can be run through an inutitive graphical user interface or command-line and requires no advanced knowledge of bioinformatics programs or scripting. Alternative regulated splicing events can be visualized in the context of proteins, domains, microRNA binding sites and using SashimiPlots in this software. For program details and to get answers to common questions, check out our Manual, Sample Data, Wiki, FAQ, Tutorials or User Group.

 

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Entertainment Content and Popular Media: The Digital Pulse of Modern Culture

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Entertainment content and popular media are the shared languages of modern society, acting as both a mirror of our current values and a driver of cultural change. While traditional forms like cinema and television remain dominant, the landscape is rapidly shifting toward digital-first, interactive experiences. Key Pillars of Modern Entertainment Entertainment Content and Popular Media: The Digital Pulse

The Evolution of Entertainment Content and Popular Media: A Comprehensive Overview Personalization : With the rise of streaming services,

The 21st century has seen a seismic shift in the way we consume entertainment content. The rise of streaming services like Netflix, Hulu, and Amazon Prime has transformed the way we watch movies and TV shows. With the ability to binge-watch entire seasons at once, viewers have more control than ever over their viewing experiences. Original content like Stranger Things (2016-present), The Crown (2016-present), and The Handmaid's Tale (2017-present) has become incredibly popular, rivaling traditional broadcast TV in terms of quality and engagement.

Social Media as Primary Source: For many, social platforms like TikTok and Instagram have surpassed traditional TV/movies in relevance.

  1. Personalization: With the rise of streaming services, viewers are increasingly expecting personalized content recommendations and tailored viewing experiences.
  2. Diversity and Representation: The entertainment industry is under pressure to better represent diverse voices and perspectives, with audiences demanding more inclusive storytelling.
  3. Immersive Experiences: VR, AR, and other immersive technologies are changing the way we experience entertainment, offering new possibilities for engagement and interaction.
  4. Social Media Influence: Social media continues to play a significant role in shaping popular culture, with influencers and content creators wielding significant influence over their followers.


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